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5th ANNUAL

BRAIN-HEART & NEUROMODULATION SYMPOSIUM

Cosmopolitan Hotel in Las Vegas, Nevada

Friday October 24 and Saturday October 25, at the Cosmopolitan of Las Vegas

Course Goal

On behalf of the Brain-Heart & Neuromodulation Symposium Planning Committe, we wish to welcome you to join us at the upcoming 5th Annual Brain-Heart & Neuromodulation Symposium, scheduled for October 25th, 2025, at the Cosmopolitan Hotel in Las Vegas, Nevada.

We are once again proud to host this prestigious event, reflecting our shared commitment to excellence in education and advancing the fields of cardiac electrophysiology, neurology and neurocardiology. The Brain and Heart Symposium is a unique conference dedicated to neurocardiology and neuromodulation and has played a pivotal role in fostering collaboration between the cardiology and neurology communities. This forum brings together clinicians, researchers, and thought leaders to explore innovations that shape the future of patient care.

Course Learning Objectives

At the conclusion of this education, the participant will be able to:

• Improve their comprehension of brain heart interactions in health and disease. • Understand the autonomic influences on the heart in patients with cardiac arrhythmias, as well as inpatients with heart failure.
• Be able to apply principles of neuromodulation in the treatment of patients with cardiac disease.

Course Information

This years Symposium will take place in Las Vegas, Nevada at the Cosmopolitan of Las Vegas on October 25th. 

Registration Information

ATTENDEE TYPE PRICE
In-person Physician Admission with CME Credits $100.00
Virtual Physician Admission with CME Credits $90.00
Virtual and In-Person Nurses Admission with CNE Credits Free
Virtual General Admission (No CME) Free
In-Person General Admission (No CME) Free

Registration fee includes: Symposium, program materials, and continuing education credits.

Refund and cancellation policy: Arizona Heart Rhythm Center reserves the right to cancel or change the program for due causes. Cancellation of this program by Arizona Heart Rhythm Center or by the participant before October 10th will result in a full refund of tuition.

Continuing Medical Education Credit Information

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the California Medical Association (CMA) through the joint providership of the University Medical Center of Southern Nevada and the Arizona Cardiovascular Research Foundation. The University Medical Center of Southern Nevada is accredited by the CMA to provide continuing medical education for physicians.

The University Medical Center of Southern Nevada designates this live educational activity for a maximum of 7 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Dinner Conference

All times refer to Las Vegas time (Pacific Daylight Time).

Friday October 24, 2025

TIME TOPIC
6:00 PM Cocktails
6:30 PM Faculty Dinner
8:00-8:30 PM Neurocardiology and Cardiac Neuromodulation: Physiologic Principles and Therapeutic Expectations: Kalyanam Shivkumar MD and Olujimi Ajijola MD
8:30-9:00 PM Discussion

Speaker Information

All times refer to Las Vegas time (Pacific Daylight Time).

Saturday October 25, 2025

TIME TOPIC
7:30 AM Registration and Vendor Exhibit
7:55 - 8:00 AM Welcome & Introduction to the 5thAnnual Brain-Heart & Neuromodulation Symposium
Robert Lemery MD, Vijendra Swarup, MD, David Wang DO, Kalyanam Shivkumar MD
 
Session I: 8:00 AM - 9:30 AM Jeff Ardell and the Human Legacy to the Physiology of the Autonomic Nervous System and the Intrinsic Cardiac Nervous System
Moderators: Kalyanam Shivkumar MD, Olujimi Ajijola MD
8:00 - 8:10 AM How About 7 Decades of Contributions to Human Physiology from the Trio of Randall-Ardell-Armour
Robert Lemery MD
8:10 - 8:20 AM Anatomy of the (Cardiac) Autonomic Nervous System
Guru Kowlgi M.B.B.S.
8:20 - 8:30 AM Physiology of the Extrinsic and Intrinsic Cardiac Nervous System
Sunny Po MD
8:30 - 8:40 AM Simultaneous Recordings of ECG and Skin Sympathetic Nerve Activity
Peng-Sheng Chen MD
8:40 - 8:50 AM Jeffrey L. Ardell, PhD.: Translational Neurocardiology. I. Contributions.
Olujimi Ajijola MD
8:50 - 9:00 AM Jeffrey L. Ardell, PhD.: Translational Neurocardiology. II. Advancements.
Olujimi Ajijola MD
9:00 - 9:10 AM Jeffrey L. Ardell, PhD.: Translational Neurocardiology. III. Future Impact.
Olujimi Ajijola MD
9:10 - 9:30 AM Panel Discussion, Q&A
9:10 - 9:30 AM Pause and Coffee Break
 
Session II. 10:00 AM - 11:30 AM Cardiac Neuromodulation Affecting Mostly SYMPATHETIC Innervation
Moderators: Robert Lemery MD, Sunny Po MD
10:00 - 10:10 AM Cardiac Sympathetic Denervation. Anatomic and Physiologic Principles During Thoracoscopic Surgical Interventions for VT/VF.
Kalyanan Shivkumar MD
10:10 - 10:20 AM Psychological and Psychiatric Outcomes Following Stellate Ganglion Block and Cardiac Sympathetic Denervation.
Sahib Khalsa MD
10:20 - 10:30 AM Sympathetic Tone and Neuropeptide Y: Culprit and Foe.
Olujimi Ajijola MD
10:30 - 10:40 AM Sympathetic Nerve Activity and ST-segment Depression.
Peng-Sheng Chen MD
10:40 - 10:50 AM Cardiac Sympathetic Denervation Targeting the Vestigial Fold in Humans.
Kalyanan Shivkumar MD
10:50 - 11:00 AM PFA and Thermal Ablation Technologies for Ablation of AF and Different Impacts on Autonomic Tone.
Guru Kowlgi M.B.B.S
11:00 - 11:10 AM Epicardial Delivery of Electroporation on the Cardiac Ganglia: PFA Does Impact Autonomic Tone.
Guru Kowlgi M.B.B.S
11:10 - 11:30 AM Panel Discussion, Q&A
 
Session III. 11:30 AM - 12:00 PM Cardiac Neuromodulation Affecting Mostly SYMPATHETIC Innervation
11:30 - 11:40 AM The Interventional Approach: Left Atrial Appendage Occlusion: PRO: Saibal Kar MD
11:40 - 11:50 AM The Pharmacologic Approach: Anticoagulants and Beyond: PRO: Arash Aryana MD
11:50 - 11:55 AM Perspective PRO Interventional: Shephal Doshi MD
11:55 - 12:00 PM Perspective PRO Pharmacology: Vijay Swarup MD
 
12:00 PM - 1:00 PM Lunch. HEART FAILURE PRIMER
Moderators: Arash Aryana MD, Sunil Kalla MD
12:10 - 12:20 PM Neuromodulation in Congestive Heart Failure: Carotid Baroreceptor Stimulation and Cardiac Contractility Modulation
David Kenigsberg MD
12:20 - 12:30 PM Leadless Pacing for Performing Conduction System Pacing
Shephal Doshi MD
12:30 - 12:40 PM Extravascular Implantable Cardioverter-Defibrillator Systems
Sudarone Thihalolipavan MD
12:40 - 12:50 PM Amyloid Disease in the Brain and Heart: Stabilizing Transthyretin Protein in Cardiac Amyloidosis
TBD MD
 
Session IV. 1:00 PM - 2:30 PM Atrial Fibrillation and the Management of Stroke
Moderators: Edip Gurol MD, Saibal Kar MD.
1:00 PM - 1:10 PM Ablation of Paroxysmal Atrial Fibrillation and Stroke Prevention
Vijay Swarup MD
1:10 PM - 1:20 PM Embolic Strokes of Unknown Source (ESUS): Controversies in Diagnosis, Risk, and Treatment
Supreet Kaur MD
1:20 PM - 1:30 PM Tailored Stroke Prevention in Atrial Fibrillation
Edip Gurol MD
1:30 PM - 1:40 PM Atrial Fibrillation and Cognition
Edip Gurol MD
1:40 PM - 1:50 PM Moving Forward: Beyond 30 years of Lytic Treatment for Acute Stroke Management
David Wang DO
1:50 PM - 2:00 PM Low-Field MRI for Diagnosis of Stroke Care: Revolutionizing Detection, Diagnosis and Intervention.
David Wang DO
2:00 PM - 2:10 PM The Ambulatory Surgical Center & The Management of Rhythm Disorders: A New Era in Clinical Cardiac Electrophysiology.
Arash Aryana MD
2:10 - 2:30 PM Panel Discussion, Q&A
2:30 - 3:00 PM Pause and Coffee Break
 
Session V. 3:00 PM - 4:30 PM Cardiac Neuromodulation Affecting Mostly PARASYMPATHETIC Innervation
Moderators: David Kenigsberg MD, David Wang DO
3:00 PM - 3:10 PM Neuromodulation for Paroxysmal AF. I. Conceptual Basis.
Peng-Sheng Chen MD
3:10 PM - 3:20 PM Neuromodulation for AF. II. Tragus Nerve Stimulation and Cardioneural Ablation for Paroxysmal AF and Post-Operative AF.
Sunny Po MD
3:20 PM - 3:30 PM Neuromodulation for Syncope. I. Conceptual Basis.
Sri Sundaram MD
3:30 PM - 3:40 PM Neuromodulation for Syncope. II. Cardioneural Ablation. The US Registry Trial.
Sri Sundaram MD
3:40 PM - 3:50 PM Outcomes of Neuromodulation Interventions: Nuclear Imaging of the Cardiac Autonomic Nervous System
Robert Lemery MD
3:50 PM - 4:00 PM Cardiac Interoception and Neuromodulation
Sahib Khalsa MD
4:00 PM - 4:10 PM Cardiac Neuromodulation: A Fine Balancing Act.
Kalyanan Shivkumar MD
4:10 PM - 4:30 PM Panel Discussion, Q&A
 
Session VI. 4:30 PM - 5:00 PM NIH and INDUSTRY Sponsored Trials: NEW and UPCOMING
Moderators: Peng-Sheng Chen MD, Kalyanan Shivkumar MD
4:30 - 4:35 PM Research Study I
4:35 - 4:40 PM Research Study II
4:40 - 4:45 PM Research Study III
4:45 - 4:50 PM Research Study IV
4:50 - 4:55 PM Research Study V
4:55 - 5:00 PM Summary
 
5:05 PM Meeting Adjourns.
5:05 - 6:00 PM Refreshments and Snacks

Course Directors

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Dr. Swarup, MD
FACC, FHRS
Co-Director
ARIZONA HEART RHYTHM CENTER

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Dr. Lemery, MD, MA
FACC, FHRS

Co-Director
ARIZONA HEART RHYTHM CENTER
Cardiac EP & Medical Historian
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Dr. Wang, DO
FAAN, FAHA
CO-DIRECTOR
HONOR-HEALTH NEUROLOGY
Bob Bové Neuroscience Institute
KALYANAM SHIVKUMAR, MD, PhD
Dr. Shivkumar, MD, PhD
FACC, FHRS
CO-DIRECTOR
DISTINGUISHED PROFESSOR
University of California, Los Angeles
2024 Commercial Promotion

• Boston Scientific (Education Grant)
• Boston Scientific (Platinum)
• Alexion Pharmaceuticals Andexxa AstraZeneca Brillanta Pharmaceutical (Gold)
• MedTronic – CRDM and Diagnostics (Silver)
• Abbott (Bronze)
• Frazer (Bronze)
• V-Wave (Bronze)

2024 Exhibitors and Sponsors

Barrow Neurological Institute wishes to recognize and thank the following companies for their commercial promotion of this educational activity.

Educational Grant:
• Boston Scientific

Platinum Exhibitor:
• Boston Scientific

Gold Exhibitor:
• AstraZeneca

Silver Exhibitor:
• MedTronic

Bronze Exhibitor:
• Frazer • V-WAVE Medical
• Abbott
Participating Sponsor Exhibitor:
• Boehringer Ingelheim • Barrow Neurological Institute’s Emergency Stroke Treatment Unit